Custom iPS Cell Reprogramming by mRNA {{ currentPage ? currentPage.title : "" }}

The derivation of iPSCs sparked widespread enthusiasm for the development of new models of human disease, enhanced platforms for drug discovery and more widespread use of autologous cell-based therapy. The emergence of reprogramming technology enabled the use of disease-specific iPSCs in established directed-differentiation protocols. Improvements in reprogramming methodologies have increased the efficiency of iPSC derivation and the quality of iPSC lines in use. Noncorrected cells differentiated from patient-derived iPSCs have been used in drug screening. Currently, a handful of candidate drugs identified in iPSC-based systems are under study in human trials.

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